Classic and contemporary imaging of coccidioidomycosis

AJR Am J Roentgenol. 1981 Feb;136(2):393-404. doi: 10.2214/ajr.136.2.393.


Disseminated coccidioidomycosis should be considered as a diagnostic possibility whenever a patient has visited or resides in an endemic coccidioidal area and has a history of fever, skin rash, persistent pulmonary symptoms, bone pain, headache, or confusion. Imaging of this multisystem disease, especially of the lung, bone, and central nervous system, shows various protean manifestations that can simulate many infectious entities. The radiographic, scintigraphic, computed tomographic, or sonographic findings of this disease may be helpful in diagnosis, prognosis, and treatment follow-up in patients with disseminated coccidioidomycosis.

Publication types

  • Review

MeSH terms

  • Amphotericin B / therapeutic use
  • Angiography
  • Cerebral Ventriculography
  • Coccidioidomycosis / complications
  • Coccidioidomycosis / diagnostic imaging*
  • Coccidioidomycosis / drug therapy
  • Ependymoma / diagnostic imaging
  • Ependymoma / pathology
  • Humans
  • Hydrocephalus / complications
  • Hydrocephalus / diagnostic imaging
  • Knee / diagnostic imaging
  • Knee / pathology
  • Lung Diseases, Fungal / complications
  • Lung Diseases, Fungal / diagnostic imaging
  • Lung Diseases, Fungal / drug therapy
  • Meningitis / complications
  • Meningitis / diagnostic imaging
  • Myelography
  • Radionuclide Imaging
  • Tomography, X-Ray Computed*


  • Amphotericin B