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Comparative Study
. 1981 Jan 15;37(1):16-7.
doi: 10.1007/BF01965543.

Role of lactone ring of aflatoxin B1 in toxicity and mutagenicity

L S Lee, J J Dunn, A J DeLucca, A Ciegler
Comparative Study

Role of lactone ring of aflatoxin B1 in toxicity and mutagenicity

L S Lee et al. Experientia. .

Abstract

Cleavage of the lactone ring of aflatoxin B1 results in a nonfluorescent compound that has greatly reduced biological activity. Mutagenicity, as measured by the Ames test, is reduced 450-fold compared to that of B1, and toxicity, as measured by the chick embryo test, is reduced 18-fold.

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References

    1. Lloydia. 1975 Jan-Feb;38(1):21-35 - PubMed
    1. Proc Natl Acad Sci U S A. 1976 Jul;73(7):2241-4 - PubMed
    1. Mutat Res. 1975 Dec;31(6):347-64 - PubMed
    1. Life Sci. 1973 Oct 16;13(8):1143-9 - PubMed
    1. Mutat Res. 1978 Nov;58(2-3):193-203 - PubMed

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