Regression of aflatoxin B1-induced hepatocellular carcinomas by reduced glutathione

Science. 1981 May 1;212(4494):541-2. doi: 10.1126/science.6782675.


Reduced glutathione administered to rats bearing aflatoxin B1-induced liver tumors caused regression of tumor growth and resulted in survival of the animals. since glutathione is a harmless natural product, it merits further investigation as a potential antitumor drug for humans.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aflatoxin B1
  • Aflatoxins*
  • Animals
  • Female
  • Glutathione / therapeutic use*
  • Liver Neoplasms, Experimental / drug therapy*
  • Liver Neoplasms, Experimental / pathology
  • Rats


  • Aflatoxins
  • Aflatoxin B1
  • Glutathione