Abstract
The structure of the bile acids in serum of infants with coprostanic acidemia was further investigated. The identity of 3 alpha-hydroxy-5 beta-cholestan-26-oic acid and 3 beta-hydroxy-5-cholesten-26-oic acid was confirmed. The biosynthesis of the 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-C29 dicarboxylic bile acid does not start from beta-sitosterol.
MeSH terms
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Acidosis / blood*
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Bile Acids and Salts / blood*
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Chemical Phenomena
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Chemistry
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Cholestanol / metabolism*
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Cholestanols / biosynthesis
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Cholestanols / blood
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Cholesterol / analogs & derivatives*
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Cholesterol / blood
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Humans
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Infant
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
Substances
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3,7,12-trihydroxycholestan-26,29-dioic acid
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3-hydroxycholestan-26-oic acid
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Bile Acids and Salts
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Cholestanols
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3-hydroxy-5-cholestenoic acid
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Cholestanol
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Cholesterol