Alginate synthesis in mucoid Pseudomonas aeruginosa: a chromosomal locus involved in control

J Gen Microbiol. 1980 Aug;119(2):443-50. doi: 10.1099/00221287-119-2-443.


Mucoid variants of Pseudomonas aeruginosa isolated in vitro or in vivo could be classified into two phenotypic groups based on whether alginate was produced on a chemically defined medium. Mucoid strains yielded lowe recombination frequencies than the non-mucoid parent when used as donors in FP2-mediated plate matings. The mucoid characteristic (muc) was co-inherited by a proportion of recombinants selected for the inheritance of chromosomal markers his-5075+ or cys-5605+. The results of further experiments using either a mucoid recipient or a mucoid donor carrying plasmid R68.45 suggested that the control of alginate production in P. aeruginosa involves at least one chromosomal locus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alginates / metabolism*
  • Chromosome Mapping
  • Genetic Linkage
  • Genetic Markers
  • Phenotype
  • Pseudomonas aeruginosa / genetics*
  • Pseudomonas aeruginosa / metabolism
  • Recombination, Genetic


  • Alginates
  • Genetic Markers