[Therapeutic comparison of throat lozenges (author's transl)]

MMW Munch Med Wochenschr. 1981 May 1;123(18):745-7.
[Article in German]


The efficacy of two commercially available throat lozenges (test preparation with lysozyme, papain and bacitracin as active ingredients, comparative preparation with a disinfectant only) has been tested under conditions of a randomized clinical study. Two groups of 50 patients each with the indications pharyngitis and/or tonsillitis, acute or subacute, have been compared under the conditions of an ENT-practice. The efficacy of the test preparation was established by the general amelioration evaluated by physician and patient and the symptoms reddening, swelling and coating of the throat, pain on swallowing and hoarseness, swelling and pain of lymph nodes. It is supposed that this superiority is due to the enzyme lysozyme and papain in the test preparation.

Publication types

  • Clinical Trial
  • Comparative Study
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Anti-Infective Agents, Local / therapeutic use*
  • Bacitracin / therapeutic use*
  • Drug Therapy, Combination
  • Female
  • Hoarseness / drug therapy
  • Humans
  • Male
  • Muramidase / therapeutic use*
  • Papain / therapeutic use*
  • Pharyngitis / drug therapy*
  • Tonsillitis / drug therapy


  • Anti-Infective Agents, Local
  • Bacitracin
  • Muramidase
  • Papain