Use of intravenous iron dextran injection in children receiving total parenteral nutrition

Am J Dis Child. 1981 Sep;135(9):829-31. doi: 10.1001/archpedi.1981.02130330039012.

Abstract

We conducted studies using intravenous (IV) iron dextran injection in 14 hospitalized infants and children with iron deficiency who required total parenteral nutrition. A single, total dose of IV iron dextran was administered during a two-hour period (preceded by a test dose of 25 mg). Doses administered ranged from 50 to 782 mg, with an average dose of 15.2 mg/kg body weight. No adverse reactions were noted during the test dose or infusion. The IV administration of iron dextran appears to be a safe method of treatment for iron repletion in children who are unable to tolerate feedings as a result of malabsorption, inflammatory bowel disease, or chronic debilitating diseases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anemia, Hypochromic / drug therapy
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Injections, Intravenous
  • Iron-Dextran Complex / administration & dosage
  • Iron-Dextran Complex / therapeutic use*
  • Male
  • Parenteral Nutrition*
  • Parenteral Nutrition, Total*

Substances

  • Iron-Dextran Complex