Comparative Effects of Carrageenan on Systemic Candidiasis and Listeriosis in Mice

Clin Exp Immunol. 1981 May;44(2):355-8.

Abstract

Carrageenan, a toxic substance for the mononuclear phagocyte system (MPS), increase drastically the susceptibility of mice against Listeria monocytogenes challenge but induces concurrently an increasing resistance against systemic candidiasis and granulocytosis. These results corroborate the minor role played by MPS and suggest that polymorphonuclear cells play a major role in non-specific resistance of mice against systemic candidiasis.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Candida albicans / isolation & purification
  • Candidiasis / immunology*
  • Candidiasis / microbiology
  • Candidiasis / prevention & control
  • Carrageenan / pharmacology*
  • Female
  • Granulocytes / immunology
  • Leukocyte Count
  • Listeria monocytogenes / isolation & purification
  • Listeriosis / immunology*
  • Listeriosis / microbiology
  • Liver / microbiology
  • Mice
  • Neutrophils / immunology
  • Phagocytes / immunology
  • Spleen / microbiology

Substances

  • Carrageenan