Inhibitors of purine nucleoside phosphorylase, C(8) and C(5') substitutions

Biochem Pharmacol. 1982 Jan 15;31(2):163-71. doi: 10.1016/0006-2952(82)90206-4.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cells, Cultured
  • Chromatography, High Pressure Liquid
  • Erythrocytes / enzymology
  • Guanine / analogs & derivatives
  • Guanine / pharmacology
  • Guanosine / analogs & derivatives
  • Guanosine / metabolism
  • Guanosine / pharmacology
  • Humans
  • In Vitro Techniques
  • Inosine / metabolism
  • Kinetics
  • Pentosyltransferases / antagonists & inhibitors*
  • Purine-Nucleoside Phosphorylase / antagonists & inhibitors*
  • Sarcoma 180 / enzymology
  • Structure-Activity Relationship
  • Substrate Specificity

Substances

  • Guanosine
  • 8-aminoguanine
  • 8-aminoguanosine
  • Inosine
  • Guanine
  • Pentosyltransferases
  • Purine-Nucleoside Phosphorylase