Chronic radiation myelitis

Radiology. 1982 Aug;144(3):609-12. doi: 10.1148/radiology.144.3.6808557.


From March 1971 to September 1973, 200 patients with primary bronchogenic carcinoma received 4,000 rad (40 Gy) by means of split-course accelerated fractionation. Forty-five patients (22.5%) survived more than 11 months; and of these, 6 (13.3%) were found to have progressive myelitis. Recent reports indicate that rapid fractionation is preferred in some centers and may be undergoing a resurgence. The authors review their experience with this technique and the current understanding of the factors which affect the development of radiation myelitis.

MeSH terms

  • Carcinoma, Bronchogenic / radiotherapy
  • Humans
  • Lung Neoplasms / radiotherapy
  • Myelitis / etiology*
  • Radiation Injuries / etiology*
  • Radiotherapy, High-Energy / adverse effects*
  • Retrospective Studies