Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding

Nature. 1982 Oct 21;299(5885):756-8. doi: 10.1038/299756a0.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphate / metabolism*
  • Amino Acyl-tRNA Synthetases / genetics*
  • Base Sequence
  • Binding Sites
  • Cysteine
  • Genes, Bacterial
  • Genetic Engineering*
  • Geobacillus stearothermophilus / enzymology
  • Mutation
  • Serine
  • Structure-Activity Relationship
  • Tyrosine-tRNA Ligase / genetics*

Substances

  • Serine
  • Adenosine Triphosphate
  • Amino Acyl-tRNA Synthetases
  • Tyrosine-tRNA Ligase
  • Cysteine