Metabolic activation of ftorafur [R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil]: the microsomal oxidative pathway

Biochem Pharmacol. 1982 Sep 15;31(18):3006-8. doi: 10.1016/0006-2952(82)90279-9.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Biotransformation
  • Cytochrome P-450 Enzyme System / metabolism
  • Fluorouracil / analogs & derivatives*
  • Fluorouracil / metabolism
  • In Vitro Techniques
  • Male
  • Microsomes, Liver / metabolism*
  • Oxidation-Reduction
  • Rabbits
  • Tegafur / metabolism*

Substances

  • Tegafur
  • Cytochrome P-450 Enzyme System
  • Fluorouracil