Failure of intensive care unit support to influence mortality from pneumococcal bacteremia

JAMA. 1983 Feb 25;249(8):1055-7.


One hundred thirty-four consecutive cases of pneumococcal bacteremia observed during a six-year period were evaluated. One hundred nineteen (89%) were associated with pneumonia. Factors associated with increased mortality were advanced age, a leukocyte count at admission of less than 5,000/cu mm, neoplastic disease, and involvement of two or more pulmonary lobes in patients with pneumonia. Mortality was 30.5% overall, and 76% in patients admitted to the intensive care unit with pneumococcal bacteremia. Pneumococcal infection continues to be an important cause of morbidity and mortality despite modern supportive care and antimicrobial therapy.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Hospital Bed Capacity, 100 to 299
  • Humans
  • Intensive Care Units*
  • Leukopenia / complications
  • Life Support Care
  • Middle Aged
  • Pneumococcal Infections / mortality*
  • Pneumonia, Pneumococcal / complications
  • Pneumonia, Pneumococcal / drug therapy
  • Pneumonia, Pneumococcal / mortality
  • Sepsis / complications
  • Sepsis / drug therapy
  • Sepsis / mortality*
  • Washington


  • Anti-Bacterial Agents