Sleep architecture and REM sleep measures in prepubertal major depressives. Studies during recovery from the depressive episode in a drug-free state

Arch Gen Psychiatry. 1983 Feb;40(2):187-92. doi: 10.1001/archpsyc.1983.01790020085008.


The sleep of 28 fully recovered, drug-free, prepubertal patients with major depressive disorder was recorded for three consecutive nights in the laboratory. Recovered depressives had significantly shorter first rapid eye movement period (REMP) latencies and a higher number of REMPs compared with themselves when depressed and with nondepressed neurotic and normal children. In addition, most sleep continuity measures improved considerably on recovery. We suggest that a short first REMP latency may be a marker of past episode or of trait in prepubertal major depressives.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Age Factors
  • Child
  • Child Development / physiology
  • Depressive Disorder / physiopathology*
  • Depressive Disorder / psychology
  • Female
  • Humans
  • Male
  • Neurotic Disorders / physiopathology
  • Psychiatric Status Rating Scales
  • Puberty
  • Sleep / physiology*
  • Sleep, REM / physiology*