Lidocaine toxicity from topical mucosal application. With a review of the clinical pharmacology of lidocaine

Clin Pediatr (Phila). 1983 Mar;22(3):190-2. doi: 10.1177/000992288302200306.


A case is reported of an infant who experienced seizures while being treated with a topical lidocaine 2% solution (Xylocaine 2% Viscous) for teething. The pharmacology of lidocaine is reviewed to alert physicians to the potential dangers of topical mucosal application of these preparations.

Publication types

  • Case Reports

MeSH terms

  • Anesthesia, Local
  • Gingiva
  • Humans
  • Infant
  • Lidocaine / administration & dosage
  • Lidocaine / adverse effects*
  • Male
  • Seizures / chemically induced*
  • Tooth Eruption


  • Lidocaine