Effects of cigarette smoking on fasting triglyceride, total cholesterol, and HDL-cholesterol in women

Am Heart J. 1983 Mar;105(3):417-21. doi: 10.1016/0002-8703(83)90358-7.


We examined the relationships of cigarette smoking with fasting triglycerides, total cholesterol, and high-density lipoprotein cholesterol (HDL-C) levels among a group of 191 white women aged 20 to 40 years. The mean triglyceride level among current smokers was 100.0 mg/100 ml and among nonsmokers was 68.4 mg/dl (p less than 0.005). Mean total cholesterol values among current smokers and nonsmokers were, respectively, 197.0 and 189.1 mg/dl (p less than 0.1). Mean HDL-C levels were 45.0 mg/dl among women who were smoking and 52.1 mg/dl among nonsmokers (p less than 0.005). Simultaneous adjustments for the effects of age, weight, height, blood glucose, resting pulse, and oral contraceptive use did not materially alter these relationships. A modest portion of the effect of cigarette smoking on risk of coronary heart disease may be explained by an adverse effect of cigarette smoking on blood lipids.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Age Factors
  • Alcohol Drinking
  • Blood Glucose / analysis
  • Body Height
  • Body Weight
  • Cholesterol / blood*
  • Cholesterol, HDL
  • Contraceptives, Oral / pharmacology
  • Fasting
  • Female
  • Humans
  • Lipoproteins, HDL / blood
  • Pulse
  • Smoking*
  • Triglycerides / blood*


  • Blood Glucose
  • Cholesterol, HDL
  • Contraceptives, Oral
  • Lipoproteins, HDL
  • Triglycerides
  • Cholesterol