Serum immunoglobulins and uveitis

Arch Ophthalmol. 1983 Mar;101(3):458-9. doi: 10.1001/archopht.1983.01040010458025.


Sixty-two percent of 975 uveitis patients had a statistically significant elevation in the levels of one or more of three serum immunoglobulins. The percentage of cases of above-normal values was greatest for IgM (43.8%), followed by IgA (34.0%), and then by IgG (11.9%). There was no statistically significant difference in immunoglobulin values obtained for one diagnosis as compared with all others, except for men with HLA-B27. They had a higher percent of elevated IgM values than men with all other diagnoses. Testing for immunoglobulins is of little or no value in the etiologic diagnosis of a single case of uveitis, but may be of value in research studies to better understand its pathogenesis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Humans
  • Immunoglobulin A / analysis
  • Immunoglobulin G / analysis
  • Immunoglobulin M / analysis
  • Immunoglobulins / analysis*
  • Male
  • Uveitis / immunology*


  • Immunoglobulin A
  • Immunoglobulin G
  • Immunoglobulin M
  • Immunoglobulins