Prognostic value of exercise thallium-201 imaging in patients presenting for evaluation of chest pain

J Am Coll Cardiol. 1983 Apr;1(4):994-1001. doi: 10.1016/s0735-1097(83)80100-4.


Accurate prognostic information is important in determining optimal management of patients presenting for evaluation of chest pain. In this study, the ability of exercise thallium-201 myocardial imaging to predict future cardiac events (cardiovascular death or nonfatal myocardial infarction) was correlated with clinical, coronary and left ventricular angiographic and exercise electrocardiographic data in 139 consecutive, nonsurgically managed patients followed-up over a 3 to 5 year period (mean follow-up, 3.7 +/- 0.9), using a logistic regression analysis. Among patients without prior myocardial infarction (100 of 139), the number of myocardial segments with transient thallium-201 defects was the only statistically significant predictor of future cardiac events when all patient variables were evaluated. Among patients with myocardial infarction before evaluation (39 of 139), angiographic ejection fraction was the only significant predictor of future cardiac events when all variables were considered. This study suggests an approach to evaluate the risk of future cardiac events in patients with possible ischemic heart disease.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Arterial Occlusive Diseases / complications
  • Arterial Occlusive Diseases / diagnostic imaging
  • Coronary Disease / complications
  • Coronary Disease / diagnosis
  • Coronary Disease / diagnostic imaging*
  • Electrocardiography
  • Exercise Test
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / diagnostic imaging
  • Myocardial Infarction / etiology
  • Pain / diagnosis
  • Pain / diagnostic imaging*
  • Pain / etiology
  • Prognosis
  • Radiography
  • Radioisotopes*
  • Radionuclide Imaging
  • Thallium*
  • Thorax


  • Radioisotopes
  • Thallium