Hemostasis and intracranial surgery

J Neurosurg. 1983 May;58(5):693-8. doi: 10.3171/jns.1983.58.5.0693.


Preoperative and postoperative coagulation studies were performed in 25 patients undergoing various intracranial surgical procedures. Coagulation abnormalities, mostly consisting of an increase of fibrin/fibrinogen degradation product concentration, either appeared or increased postoperatively in 18 patients. This incidence of postoperative appearance or increase of coagulation abnormalities is higher than that reported in a comparable study of patients after general surgical procedures, and also higher than that of coagulation abnormalities in a previous study of patients after blunt head injury. Although the coagulation abnormalities after intracranial surgery were usually small, they tended to be larger in patients with more extensive intracranial procedures.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Blood Coagulation Disorders / blood*
  • Brain Diseases / surgery*
  • Child
  • Female
  • Fibrin Fibrinogen Degradation Products / analysis*
  • Fibrinolysis*
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications*


  • Fibrin Fibrinogen Degradation Products