Effects of [Ca2+]o on Contractility in the Anoxic Cardiac Muscle of Mammal and Fish

Life Sci. 1983 Mar 28;32(13):1437-42. doi: 10.1016/0024-3205(83)90908-6.


Electrically paced atrial strips of hearts from rat and rainbow trout were exposed to increasing extracellular Ca2+ concentration, [Ca2+]o. This resulted in increases in the peak force in oxygenated atria from both species. During anoxia this response was suppressed for the rat, but accentuated for trout atrium.

MeSH terms

  • Animals
  • Calcium / pharmacology*
  • Heart / physiopathology*
  • Heart Atria / physiopathology
  • Hypoxia / physiopathology*
  • Myocardial Contraction / drug effects*
  • Rats
  • Stimulation, Chemical
  • Trout


  • Calcium