Stratified trend and homogeneity analyses of proportions and life table data

Comput Biomed Res. 1983 Apr;16(2):116-26. doi: 10.1016/0010-4809(83)90012-5.


Tests for linear trend and homogeneity among proportions and analogous time adjusted tests for life table data are programmed for stratified data. For proportions, the maximum likelihood estimator of the common logistic slope and its approximate standard error is given. This parameter is related to the relative risk for the factor under test. The model is a simpler and more relevant subcase of the general linear multiple logistic model. Tests of fit include a chi-square test of departure from trend for both types of data, and, for proportions, a test for the equality of slopes among groups of strata. The program is particularly useful for large prospective studies in epidemiology, but may also prove helpful for case-control studies, clinical trials, and combining animal studies. Several optional analyses are included. The program generalizes most aspects of a previously published program by Thomas, Breslow, and Gart (Trend and homogeneity analyses of proportions and life table data. Comp. Biomed. Res. 10, 373 (1977)). A FORTRAN card deck with documentation is available upon request.

MeSH terms

  • Actuarial Analysis*
  • Analysis of Variance
  • Humans
  • Lung Neoplasms / etiology
  • Models, Biological
  • Smoking