Inhibitory influence of unstimulated rods in the human retina: evidence provided by examining cone flicker

Science. 1983 Jul 8;221(4606):180-2. doi: 10.1126/science.6857279.


In the parafoveal retina of human observers, cone-mediated sensitivity to flicker decreases as rods become progressively more dark-adapted. This effect is greatest when a rod response to flicker is precluded. These results indicate that rods tonically inhibit cone pathways in the dark.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Dark Adaptation
  • Flicker Fusion / physiology
  • Humans
  • Neural Inhibition
  • Photoreceptor Cells / physiology*
  • Retina / physiology*