C3b receptors on human glomeruli in vitro. Loss in culture

Am J Pathol. 1978 Jul;92(1):147-54.

Abstract

C3b receptors, easily demonstrated on isolated human infant glomeruli, are lost as cells grow in culture. This suggests that epithelial cells are dedifferentiated or that the C3b receptor is not intrinsic to the epithelial cell.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Cells, Cultured
  • Complement C3
  • Epithelial Cells
  • Humans
  • Kidney Glomerulus / analysis
  • Kidney Glomerulus / cytology
  • Kidney Glomerulus / immunology*
  • Receptors, Drug / analysis*

Substances

  • Complement C3
  • Receptors, Drug