Spontaneous regression of stage IV neuroblastoma

Acta Paediatr Scand. 1983 May;72(3):473-6. doi: 10.1111/j.1651-2227.1983.tb09752.x.


Neuroblastoma presenting with wide spread osseous metastases (stage IV) is generally considered incurable. However, rare cases of spontaneous regression and cure are on record. This report deals with such a case in which an infant received steroids as sole treatment for developing skeletal pain. Established metastases to the brain, scalp and skeleton disappeared. Today 4 1/2 years later the patient is free from symptoms and signs of tumour.

Publication types

  • Case Reports

MeSH terms

  • Bone Neoplasms / secondary
  • Brain Neoplasms / secondary
  • Child, Preschool
  • Head and Neck Neoplasms / secondary
  • Humans
  • Male
  • Neuroblastoma / pathology*
  • Remission, Spontaneous