Celiac disease in monozygous twin boys. Asynchronous presentation

Dig Dis Sci. 1982 Dec;27(12):1137-40. doi: 10.1007/BF01391454.


A 13-year-old boy presented when his weight gain fell behind that of his monozygous twin brother. Following investigation, he was found to have gluten-sensitive enteropathy on jejunal biopsy. Investigation of his symptom-free brother showed biopsy evidence of the condition with changes similar to those of the clinically affected boy. Following treatment with a gluten-free diet, the boys achieved a similar weight after 15 months.

MeSH terms

  • Adolescent
  • Biopsy
  • Body Weight
  • Celiac Disease / diagnosis
  • Celiac Disease / diet therapy
  • Celiac Disease / genetics*
  • Diseases in Twins*
  • Female
  • Glutens / administration & dosage
  • Humans
  • Hyperplasia
  • Jejunum / pathology
  • Male
  • Pregnancy
  • Time Factors
  • Twins, Monozygotic


  • Glutens