Metabolism of 6-chlorotryptophan to 4-chloro-3-hydroxyanthranilic acid: a potent inhibitor of 3-hydroxyanthranilic acid oxidase

Arch Biochem Biophys. 1980 Aug;203(1):161-6. doi: 10.1016/0003-9861(80)90164-2.
No abstract available

MeSH terms

  • 3-Hydroxyanthranilic Acid / analogs & derivatives
  • 3-Hydroxyanthranilic Acid / biosynthesis*
  • 3-Hydroxyanthranilic Acid / pharmacology
  • 3-Hydroxyanthranilic Acid / urine
  • Animals
  • Guinea Pigs
  • Kinetics
  • Liver / drug effects
  • Liver / enzymology
  • Male
  • Oxidoreductases / antagonists & inhibitors*
  • Rats
  • Sweetening Agents / metabolism*
  • Sweetening Agents / pharmacology
  • Tryptophan / analogs & derivatives*
  • Tryptophan / metabolism
  • Tryptophan / pharmacology
  • ortho-Aminobenzoates / biosynthesis*

Substances

  • Sweetening Agents
  • ortho-Aminobenzoates
  • 6-chlorotryptophan
  • 3-Hydroxyanthranilic Acid
  • 4-chloro-3-hydroxyanthranilic acid
  • Tryptophan
  • Oxidoreductases
  • 3-hydroxyanthranilic acid oxidase