Abstract
Changes of the complement components in the sera of 13 children with treated coeliac disease were studied after gluten challenge. The levels of C 1 and C3-activator (factor B) were significantly decreased at 4 h after the challenge, as were the levels of total complement (CH 50) and the components C 1, C 4 and C 1-inactivator at 8 h. After 24 h most values returned to normal but there was another significant decrease in serum C 4 after 24 h, and for CH 50, C 1, C 2 and C 4 after 48 h.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Celiac Disease / diet therapy
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Celiac Disease / immunology*
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Child
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Child, Preschool
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Complement C1 / analysis
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Complement C1 Inactivator Proteins / analysis
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Complement C3-C5 Convertases / analysis
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Complement C4 / analysis
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Complement System Proteins / analysis*
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Female
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Glutens*
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Humans
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Male
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Time Factors
Substances
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Complement C1
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Complement C1 Inactivator Proteins
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Complement C4
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Glutens
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Complement System Proteins
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Complement C3-C5 Convertases