Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-alpha

Nature. 1978 Oct 5;275(5679):458-60. doi: 10.1038/275458a0.
No abstract available

MeSH terms

  • Cell Division / drug effects
  • DNA Replication / drug effects
  • Diterpenes / pharmacology*
  • Meiosis / drug effects
  • Mitosis / drug effects*
  • Nucleic Acid Synthesis Inhibitors*
  • Protein Biosynthesis / drug effects
  • Sea Urchins / drug effects
  • Sea Urchins / metabolism
  • Species Specificity
  • Starfish / drug effects

Substances

  • Diterpenes
  • Nucleic Acid Synthesis Inhibitors