Abnormalities in the macroscopically normal white matter in cases of mild or spinal multiple sclerosis (MS)

Acta Neuropathol Suppl. 1981;7:176-8. doi: 10.1007/978-3-642-81553-9_53.

Abstract

In a study of a series of mild and spinal varieties of multiple sclerosis the following histological changes have been found in the macroscopically normal white matter: 1. Marked astrocytic proliferation. 2. Some sclerosis of blood vessels. 3. Some perivascular inflammation. 4. Occasional unsuspected demyelination.

MeSH terms

  • Aged
  • Brain / pathology
  • Female
  • Gliosis / pathology
  • Humans
  • Male
  • Middle Aged
  • Multiple Sclerosis / pathology*
  • Myelin Sheath / ultrastructure
  • Spinal Cord / pathology