A review on fluoride varnishes: an alternative topical fluoride treatment

Community Dent Oral Epidemiol. 1982 Jun;10(3):117-23. doi: 10.1111/j.1600-0528.1982.tb01334.x.


The in vitro, in vivo and clinical research on topical fluoride varnishes in surveyed. The probable mechanisms of action for fluoride varnishes is discussed and this effect demonstrated from the results of in vitro and in vivo research. Findings from clinical studies are summarized and selected results are used to estimate expected preventive effects from the treatment. The practical advantages and limitations of fluoride varnishes are also reviewed and indications for the future used of these preventive agents are considered.

MeSH terms

  • Adult
  • Animals
  • Child
  • Child, Preschool
  • Dental Caries / prevention & control
  • Dental Enamel / metabolism
  • Drug Combinations / metabolism
  • Fluorides, Topical / administration & dosage*
  • Fluorides, Topical / metabolism
  • Fluorides, Topical / therapeutic use
  • Humans
  • Paint
  • Polyurethanes / metabolism
  • Rats
  • Silanes / metabolism
  • Sodium Fluoride / metabolism
  • Time Factors


  • Drug Combinations
  • Fluorides, Topical
  • Polyurethanes
  • Silanes
  • sodium fluoride topical preparation
  • Fluor Protector
  • Sodium Fluoride