Age-related changes in the cornea

J Am Optom Assoc. 1980 Aug;51(8):761-5.


The optometrist observes and must distinguish between physiologic and pathologic changes in the cornea. This paper deals with normal, physiologic age-related corneal changes. Age-related changes are those that occur over the entire life span, not merely in senescence. They include changes in corneal curvature, toricity, diameter, asphericity, thickness, tactile sensitivity, and a variety of senescent changes. The senescent changes of the cornea include a reduction in epithelial luster, dellen, microcystic dystrophy, the Hudson-Stahli line, crocodile shagreen, the white limbus girdle of Vogt, an increase in stromal relucency, cornea farinata, arcus senilis, Hassall-Henle warts, guttata, a reduction in endothelial cell count and Krukenberg's spindle.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aging*
  • Arcus Senilis / etiology*
  • Child
  • Child, Preschool
  • Cornea / anatomy & histology
  • Cornea / physiology*
  • Corneal Diseases / etiology*
  • Corneal Dystrophies, Hereditary / etiology
  • Eye Diseases / etiology*
  • Humans
  • Infant
  • Infant, Newborn
  • Middle Aged
  • Touch / physiology