Radionuclide localization of lower gastrointestinal hemorrhage

Radiology. 1981 May;139(2):465-9. doi: 10.1148/radiology.139.2.6971455.


The authors prospectively evaluated the usefulness of abdominal radionuclide scintigraphy using 99mTc-labeled red cells as a means of monitoring for intermittent gastrointestinal bleeding over a 24-hour period in both control and actively bleeding populations. Of 32 patients with documented hemorrhage, 29 had positive scintiscans (sensitivity, 91%; 9% false negatives). Of 18 nonbleeding patients, 17 had negative scintiscans (specificity, 95%; 5% false positives). 12 of 29 patients bled from 6 to 24 hours after the study was begun. Scintiscans were positive in patients with transfusion requirements of greater than or equal to 500 ml/24 hr. The authors conclude that abdominal scintigraphy with 99mTc-labeled red cells is an effective method of detecting gastrointestinal bleeding.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Angiography
  • Erythrocytes*
  • False Negative Reactions
  • False Positive Reactions
  • Female
  • Gastrointestinal Hemorrhage / diagnostic imaging*
  • Humans
  • Male
  • Middle Aged
  • Radionuclide Imaging
  • Technetium*


  • Technetium