Primary immunodeficiency disorders in Sweden: cases among children, 1974-1979

J Clin Immunol. 1982 Apr;2(2):86-92. doi: 10.1007/BF00916891.

Abstract

A nationwide survey of symptomatic primary immunodeficiency disorders in children in Sweden during the 6-year period 1974-1979 resulted in 201 reported cases. The reported data for 174 children were analyzed. Antibody deficiencies were the most frequent (45.0%), followed by phagocytic disorders (22.0%) and combined T- and B-cell disorders (20.8%). Thirty-two children (18.4%) died, with the highest mortality for combined T- and B-cell defects. The sex ratio for all disorders was 2:1 for boys:girls. Neutropenia was significantly more common in the northern part of Sweden.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abnormalities, Multiple / epidemiology
  • Abnormalities, Multiple / immunology
  • Adolescent
  • Agammaglobulinemia / complications
  • Agammaglobulinemia / epidemiology
  • Ataxia Telangiectasia / complications
  • Ataxia Telangiectasia / epidemiology
  • B-Lymphocytes / immunology
  • Bacterial Infections / complications
  • Bone and Bones / abnormalities
  • Candidiasis, Chronic Mucocutaneous / complications
  • Candidiasis, Chronic Mucocutaneous / epidemiology
  • Child
  • Child, Preschool
  • Dysgammaglobulinemia / epidemiology
  • Female
  • Humans
  • IgA Deficiency
  • Immunologic Deficiency Syndromes / epidemiology*
  • Immunologic Deficiency Syndromes / immunology
  • Infant
  • Infant, Newborn
  • Male
  • Neutropenia / complications
  • Neutropenia / epidemiology
  • Sweden
  • Syndrome
  • T-Lymphocytes / immunology
  • Wiskott-Aldrich Syndrome / complications
  • Wiskott-Aldrich Syndrome / epidemiology
  • Wiskott-Aldrich Syndrome / genetics