Seasonal variation in fasting plasma glucose levels in man

Diabetologia. 1982 Apr;22(4):250-3. doi: 10.1007/BF00281300.


A Southern California community study of 4,541 men and women (aged 20-79 years) showed significant seasonal variation in fasting plasma glucose. There was a mean 0.6 mmol/l difference between highest levels in winter and lowest levels in spring. This difference was consistent over a two-year period, similar at all ages and seen in both men and women. Fasting plasma glucose levels correlated directly with percentage possible sunshine (p = 0.03) and inversely with temperature (p = 0.04). Adjustment for the level of measured obesity did not alter the observed association, but a history of recent weight gain corresponded to the season of maximum fasting plasma glucose level.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Blood Glucose / analysis*
  • Cross-Sectional Studies
  • Diet
  • Fasting*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Obesity / blood
  • Physical Exertion
  • Seasons*
  • Sex Factors


  • Blood Glucose