Pre-B cell suppression by thymoma patient lymphocytes

Clin Exp Immunol. 1982 May;48(2):437-42.


T lymphocytes from the blood of two thymoma patients with hypogammaglobulinaemia suppressed the in vitro proliferation of allogeneic pre-B cells. Both patients lacked pre-B and B cells in blood and bone marrow. It is possible that pre-B cells, as well as B cells, may be targets for suppression by T cells in thymoma patients with hypogammaglobulinaemia.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Agammaglobulinemia / complications
  • B-Lymphocytes / immunology*
  • Bone Marrow / immunology
  • Cell Division
  • Cells, Cultured
  • Humans
  • Immune Tolerance
  • Male
  • T-Lymphocytes / immunology
  • Thymoma / complications
  • Thymoma / immunology*
  • Thymus Neoplasms / complications
  • Thymus Neoplasms / immunology*