Altered 67Ga citrate distribution in patients with multiple red blood cell transfusions

AJR Am J Roentgenol. 1982 Oct;139(4):755-9. doi: 10.2214/ajr.139.4.755.


Gallium-67 citrate studies from four patients who received multiple red blood cell transfusions were reviewed. Increased kidney, bladder, or bone localization was associated with decreased liver and colon activity. The findings suggest altered distribution due to competition with iron for receptor binding. Identification of inflammatory disease in two patients was possible. However, the effect of transfusions on detection of inflammatory or neoplastic diseases requires further evaluation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Blood Transfusion*
  • Bone and Bones / diagnostic imaging
  • Bone and Bones / metabolism
  • Erythrocyte Transfusion*
  • Female
  • Gallium Radioisotopes / metabolism*
  • Humans
  • Inflammation / diagnostic imaging
  • Kidney / metabolism
  • Male
  • Neoplasms / diagnostic imaging
  • Prospective Studies
  • Radionuclide Imaging
  • Urinary Bladder / metabolism


  • Gallium Radioisotopes