Milk, serum cholesterol, and the Maasai. A hypothesis

Atherosclerosis. 1980 Mar;35(3):339-43. doi: 10.1016/0021-9150(80)90131-8.

Abstract

The Maasai of East Africa have been found to have low serum concentrations of cholesterol and a low incidence of cardiovascular disease in spite of apparently very high milk intakes. On that basis it has been frequently suggested that milk contains a "hypocholesterolaemic factor". The hypocholesterolaemia of the Maasai had also been attributed to a genetic adaptation. We feel that the milk intakes reported for the Maasai are excessively high and that the low incidence of cardiovascular diseases and low levels of serum cholesterol may be adequately explained by their variable and generally low energy intakes.

Publication types

  • Review

MeSH terms

  • Adult
  • African Americans
  • African Continental Ancestry Group*
  • Animals
  • Anticholesteremic Agents / physiology
  • Calcium, Dietary / physiology
  • Cattle
  • Cholesterol / blood*
  • Cholesterol, Dietary / pharmacology
  • Coronary Disease / blood
  • Coronary Disease / epidemiology*
  • Coronary Disease / genetics
  • Coronary Disease / urine
  • Glutarates / metabolism
  • Humans
  • Kenya
  • Male
  • Milk / physiology*
  • Orotic Acid / metabolism
  • Tanzania

Substances

  • Anticholesteremic Agents
  • Calcium, Dietary
  • Cholesterol, Dietary
  • Glutarates
  • Orotic Acid
  • Cholesterol