Sterile topical lignocaine jelly in plastic surgery: an assessment of its systemic toxicity

S Afr Med J. 1980 Apr 26;57(17):704-6.


Topical local anaesthesia offers an important adjunct to several plastic surgery procedures, provided that it does not cause systemic toxicity or prevent the healing process. Absorption of a sterile topical lignocaine jelly was assessed in patients undergoing treatment of skin graft donor sites, flap donor sites and burns. There was a marked degree of absorption only in patients with thermal burns, in which case it depended on the surface area of the wound; although no toxic effects due to absorption were noted, caution in dosage is advisable. No complications of healing attributable to the preparation used were encountered.

MeSH terms

  • Anesthesia, Local*
  • Burns / therapy*
  • Humans
  • Lidocaine / blood
  • Lidocaine / metabolism*
  • Lidocaine / urine
  • Skin Transplantation*
  • Surgery, Plastic*


  • Lidocaine