Standardized senna in the management of constipation in the puerperium: A clinical trial

S Afr Med J. 1980 Jan 19;57(3):78-80.


Successful treatment of constipation in the immediate postpartum period in 93% of White patients and 96% of Coloured patients was achieved in a clinical trial of standardized senna tablets (Senokot; Reckitt & Colman). This is significantly better than the success rates of 51% and 59% achieved in White and Coloured controls treated with a placebo. Minor abdominal cramps occurred in some 13% of the patients treated with standardized senna, and in 4% of the controls given the placebo. There is no evidence to suggest that standardized senna has any effect whatsoever on a breast-fed baby if taken by the mother.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Breast Feeding
  • Clinical Trials as Topic
  • Constipation / drug therapy*
  • Diarrhea, Infantile / chemically induced
  • Double-Blind Method
  • Female
  • Humans
  • Pregnancy
  • Puerperal Disorders / drug therapy*
  • Senna Extract / adverse effects
  • Senna Extract / therapeutic use*


  • Senna Extract