Gastric emptying of liquids and solids: roles of proximal and distal stomach

Am J Physiol. 1980 Aug;239(2):G71-6. doi: 10.1152/ajpgi.1980.239.2.G71.


The objective was to explore the hypothesis that the proximal stomach has a major role in gastric emptying of liquids and the distal stomach a major role in gastric emptying of solids. The results of experiments on the intact stomach and on the stomach after selective resections, denervations, and during hormonal infusions are, in general, consistent with the hypothesis.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Dogs
  • Gastric Emptying*
  • Gastrins / pharmacology
  • Membrane Potentials / drug effects
  • Microspheres
  • Muscle Contraction
  • Muscle, Smooth / physiology
  • Peristalsis
  • Pyloric Antrum / physiology
  • Pylorus / physiology
  • Stomach / innervation
  • Stomach / physiology*
  • Vagus Nerve / physiology


  • Gastrins