The porosity of the cell wall of Candida albicans

J Gen Microbiol. 1980 Jul;119(1):253-5. doi: 10.1099/00221287-119-1-253.

Abstract

Polyethylene glycols of different molecular sizes have been used to study the penetrability of the cell wall of Candida albicans harvested at the end of the growth phase and after prolonged incubation in the stationary phase. No differences were found which could account for the greater resistance of cells from stationary phase cultures of C. albicans to the antimycotic agents amphotericin B methyl ester and miconazole.

MeSH terms

  • Amphotericin B / pharmacology
  • Candida albicans / drug effects
  • Candida albicans / growth & development
  • Candida albicans / metabolism*
  • Cell Wall / metabolism*
  • Drug Resistance, Microbial
  • Miconazole / pharmacology
  • Permeability
  • Polyethylene Glycols / metabolism*

Substances

  • Polyethylene Glycols
  • Miconazole
  • Amphotericin B