Renal preservation with inosine

Urology. 1980 Oct;16(4):343-5. doi: 10.1016/0090-4295(80)90134-x.

Abstract

Isosine improved post-transplantation function of canine kidneys subjected to thirty minutes of normothermic ischemia followed by flushing and twenty-four-hour cold storage. Inosine was not able to improve renal preservation when cold storage was extended to forty-eight hours after thirty minutes of normothermic ischemia.

MeSH terms

  • Animals
  • Cold Temperature
  • Dogs
  • Female
  • Inosine / pharmacology*
  • Ischemia
  • Kidney / blood supply
  • Kidney / physiopathology
  • Kidney Transplantation*
  • Male
  • Organ Preservation
  • Time Factors
  • Transplantation, Autologous

Substances

  • Inosine