In vitro activation of 1,2-dichloroethane by microsomal and cytosolic enzymes

Toxicol Appl Pharmacol. 1980 Sep 15;55(2):303-17. doi: 10.1016/0041-008x(80)90092-7.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Biotransformation
  • Cytochrome P-450 Enzyme System / metabolism
  • Cytosol / enzymology*
  • DNA / metabolism
  • Ethylene Dichlorides / metabolism*
  • Hydrocarbons, Chlorinated / metabolism*
  • In Vitro Techniques
  • Male
  • Microsomes / enzymology*
  • Mutagens
  • Oxidation-Reduction
  • Protein Binding
  • Rats
  • Salmonella typhimurium / genetics

Substances

  • Ethylene Dichlorides
  • Hydrocarbons, Chlorinated
  • Mutagens
  • ethylene dichloride
  • DNA
  • Cytochrome P-450 Enzyme System