Mutagenicity of islandicin and chrysophanol in the Salmonella/microsome system

Appl Environ Microbiol. 1980 Sep;40(3):476-9. doi: 10.1128/aem.40.3.476-479.1980.

Abstract

Chrysophanol and islandicin, two anthraquinones which are structurally related to emodin, were found to be frame-shift mutagens for Salmonella typhimurium strain TA 1537 after metabolic activation.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anthraquinones / pharmacology*
  • Mutagenicity Tests
  • Mutagens*
  • Mutation
  • Salmonella typhimurium / genetics

Substances

  • Anthraquinones
  • Mutagens
  • funiculosin (anthraquinone)
  • chrysophanic acid