Abstract
A number of minor compounds were isolated from fermentations of the protorifamycin I producing strain Nocardia mediterranei F 1/24(1,2)) and identified by means of chemical and spectroscopic methods. Two types of structures were identified: Type 1: modified protorifamycins (derived from protorifamycin I) Type 2: defective rifamycins (8-deoxyrifamycins).
MeSH terms
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Anti-Bacterial Agents / biosynthesis*
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Anti-Bacterial Agents / isolation & purification
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Anti-Bacterial Agents / pharmacology
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Bacteria / drug effects
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Candida albicans / drug effects
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Chemical Phenomena
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Chemistry
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Fermentation
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Lactams, Macrocyclic
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Magnetic Resonance Spectroscopy
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Nocardia / metabolism*
Substances
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Anti-Bacterial Agents
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Lactams, Macrocyclic