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Review
, 43 (2), 153-8

[Pharmacological Properties of Sidnocarb Analogs]

[Article in Russian]
  • PMID: 7002590
Review

[Pharmacological Properties of Sidnocarb Analogs]

[Article in Russian]
R A Al'tshuler et al. Farmakol Toksikol.

Abstract

It was shown in experiments on mice and rats that increased hydrophobic properties of the phenylcarbomoyl radical to sydnocarb attained by introduction of halogens of trifluoromethylene in the benzene ring is conducive to the production of compounds that are similar to sydnocarb by the spectrum of the central stimulant action but are 2--4 times more active. In contradistinction to phenamine and its analogues the replacement of beta-phenylisopropyl chain by beta-phenylethyl one is not followed by an abrupt decrease in the activity in the series of compounds tested.

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