Use of saralasin to detect renovascular hypertension in childhood

Urology. 1980 Nov;16(5):453-6. doi: 10.1016/0090-4295(80)90593-2.

Abstract

Current methods to evaluate renovascular hypertension in the pediatric population often requires a general anesthetic. Saralasin, an angiotensin II competitive inhibitor, is a safe, noninvasive technique which can be utilized at the bedside in a salt-depleted child off antihypertensive medication. Two illustrative cases are presented.

Publication types

  • Case Reports

MeSH terms

  • Aldosterone / blood
  • Angiotensin II / analogs & derivatives*
  • Blood Pressure / drug effects
  • Child
  • Humans
  • Hypertension, Renal / diagnosis*
  • Hypertension, Renovascular / diagnosis*
  • Infusions, Parenteral
  • Male
  • Radiography
  • Renal Artery / diagnostic imaging
  • Renin / blood
  • Saralasin* / administration & dosage

Substances

  • Angiotensin II
  • Aldosterone
  • Renin
  • Saralasin