Intrachromosomal gene conversion in yeast

Nature. 1981 Jan 15;289(5794):144-8. doi: 10.1038/289144a0.


We have shown that the yeast Saccharomyces cerevisiae has a mechanism by which information from one gene can be transferred non-reciprocally to a repeated copy of the gene on the same chromosome. This intrachromosomal gene conversion may be important in maintaining sequence homogeneity within families of repeated eukaryotic genes.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Chromatids / ultrastructure
  • Chromosomes / ultrastructure*
  • DNA, Fungal / genetics
  • Gene Conversion*
  • Leucine
  • Meiosis
  • Mutation
  • Plasmids
  • Repetitive Sequences, Nucleic Acid
  • Saccharomyces cerevisiae / genetics*
  • Sister Chromatid Exchange


  • DNA, Fungal
  • Leucine