Peptidyl diazomethyl ketones are specific inactivators of thiol proteinases

J Biol Chem. 1981 Feb 25;256(4):1923-8.
No abstract available

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Affinity Labels
  • Cathepsins / antagonists & inhibitors
  • Chymotrypsin / antagonists & inhibitors
  • Cysteine Endopeptidases
  • Diazomethane / analogs & derivatives*
  • Diazomethane / chemical synthesis
  • Diazomethane / pharmacology
  • Ketones / chemical synthesis
  • Ketones / pharmacology*
  • Kinetics
  • Methods
  • Pancreatic Elastase / antagonists & inhibitors
  • Protease Inhibitors*
  • Structure-Activity Relationship
  • Thermolysin / antagonists & inhibitors
  • Trypsin Inhibitors / pharmacology

Substances

  • Affinity Labels
  • Ketones
  • Protease Inhibitors
  • Trypsin Inhibitors
  • peptidyl diazomethyl ketones
  • Diazomethane
  • Cathepsins
  • Chymotrypsin
  • Pancreatic Elastase
  • Cysteine Endopeptidases
  • Thermolysin