Prednisone and azathioprine for polymyositis: long-term followup

Arthritis Rheum. 1981 Jan;24(1):45-8. doi: 10.1002/art.1780240107.


Two groups of patients with polymyositis have been followed for approximately 3 years. One group was treated with prednisone alone and the other with prednisone plus azathioprine. Although the polymyositis of both groups has improved, no statistically significant difference was noted at the end of 3 months, as previously reported. Longer followup, however, has shown that the group given prednisone plus azathioprine has improved more with respect to functional disability; this group also requires less prednisone for disease control.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Azathioprine / adverse effects
  • Azathioprine / therapeutic use*
  • Clinical Trials as Topic
  • Follow-Up Studies
  • Humans
  • Myositis / drug therapy*
  • Prednisone / adverse effects
  • Prednisone / therapeutic use*


  • Azathioprine
  • Prednisone